BDBM258146 US9493448, 122::US9493448, 154::US9493448, 48::US9597330, Example 34::US9845313, Example 154

SMILES Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(cc1Cl)S(=O)(=O)Nc1ccncn1

InChI Key InChIKey=OJKONCJPCULNOW-DYVFJYSZSA-N

Data  32 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 258146   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM258146(US9493448, 122 | US9493448, 154 | US9493448, 48 | ...)
Affinity DataIC50:  16nMpH: 7.3 T: 2°CAssay Description:Current record was obtained by an automated patch clamp system IonWorks Quattro (Molecular Devices Corporation) in Population Patch Clamp mode. The o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM258146(US9493448, 122 | US9493448, 154 | US9493448, 48 | ...)
Affinity DataIC50:  17nMpH: 7.3 T: 2°CAssay Description:Current record was obtained by an automated patch clamp system IonWorks Quattro (Molecular Devices Corporation) in Population Patch Clamp mode. The o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM258146(US9493448, 122 | US9493448, 154 | US9493448, 48 | ...)
Affinity DataIC50:  16nMAssay Description:Current recording was obtained by an automated patch clamp system IonWorks Quattro (Molecular Devices Corporation) in Population Patch Clamp mode. Th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM258146(US9493448, 122 | US9493448, 154 | US9493448, 48 | ...)
Affinity DataIC50:  20nMAssay Description:Current recording was obtained by an automated patch clamp system IonWorks Quattro (Molecular Devices Corporation) in Population Patch Clamp mode. Th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM258146(US9493448, 122 | US9493448, 154 | US9493448, 48 | ...)
Affinity DataIC50:  16nMAssay Description:Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM258146(US9493448, 122 | US9493448, 154 | US9493448, 48 | ...)
Affinity DataIC50:  20nMAssay Description:Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM258146(US9493448, 122 | US9493448, 154 | US9493448, 48 | ...)
Affinity DataIC50:  17nMAssay Description:Current record was obtained by an automated patch clamp system “IonWorks Quattro (Molecular Devices Corporation)” in Population Patch Clamp mode. The...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM258146(US9493448, 122 | US9493448, 154 | US9493448, 48 | ...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human Nav1.7 expressed in CHO cells with -120 mV holding potential by whole cell manual patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM258146(US9493448, 122 | US9493448, 154 | US9493448, 48 | ...)
Affinity DataIC50:  20nMpH: 7.3 T: 2°CAssay Description:Current record was obtained by an automated patch clamp system IonWorks Quattro (Molecular Devices Corporation) in Population Patch Clamp mode. The o...More data for this Ligand-Target Pair
In DepthDetails US Patent